Excretion of P-nitrophenol and P-aminophenol in the Urine of a Patient Exposed to Nitrobenzene.
نویسندگان
چکیده
A 47-year-old woman, after being exposed to nitrobenzene for 17 months, was admitted to hospital because of headache, nausea, cyanosis, and general weakness. Laboratory study revealed, in addition to methaemoglobinaemia, the presence of p-aminophenol as well as p-nitrophenol in the urine. Both compounds gradually disappeared from the urine during the two weeks after she was removed from the toxic agent. The fate of methaemoglobinaemia paralleled that of these two compounds.
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(31 %), m-nitrophenol (9%), p-nitrophenol (9%), m-aminophenol (4%), o-aminophenol (3 %), 4nitrocatechol (0.7 %), aniline (033%) and o-nitrophenol (0.1%). Two new metabolites, nitroquinol (0.1%) and p-nitrophenylmercapturic acid (0.3%), were found in the urine. 4. The denitration products, phenol, catechol, L-phenylmercapturic acid, and trans-tran8-muconic acid, did not occur in the urine. 5. Ni...
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ورودعنوان ژورنال:
- British journal of industrial medicine
دوره 21 شماره
صفحات -
تاریخ انتشار 1964